SAMe is produced using medically-oriented processes, combined with methylated folate and B12 for maximum methylation support; practitioner-trusted brand.
A supplement providing 200 mg of stabilized SAMe per capsule, along with B-vitamin cofactors (B6, folate as 5-MTHF, B12) to support methylation pathways, liver and brain health, mood balance, neurotransmitter synthesis and cellular metabolism.
The HUM2N Difference
- Third-party tested for purity & performance
- Developed with clinical insight from 10,000+ patients
- The same protocols used in our clinic, now made for home
SAMe
A supplement providing 200 mg of stabilized SAMe per capsule, along with B-vitamin cofactors (B6, folate as 5-MTHF, B12) to support methylation pathways, liver and brain health, mood balance, neurotransmitter synthesis and cellular metabolism.
Dispatched within 24 hours. Tracked, reliable delivery across the UK in 1–2 working days.
FAST UK delivery in 1–2 BUSINESS days
CHAT & EMAIL SUPPORT
30-DAY CLINICAL RESULTS GUARANTEE
Free shipping & returns
We stand by the quality of HUM2N supplements. We offer free shipping and hassle-free returns on all unopened products.
If something isn’t right, just reach out—we're here to help.
why SAMe
How to use SAMe
When to Use
Your Questions, Answered
Frequently asked questions
What is SAMe and why take it?
A natural compound that supports mood, liver health and methylation.
When should I take it and does it matter with food?
Take 1 capsule daily on an empty stomach; with a light snack if sensitive.
Is it suitable for vegetarians or vegans?
Yes — vegetarian-friendly and free from gluten, dairy and soy.
Can I take it with other mood or liver supplements?
Usually safe, but check with your practitioner before combining with mood-related products.
Are there any contraindications?
Consult your doctor if pregnant, on antidepressants, or managing bipolar disorder.
Uncompromising Quality.
Gluten-free
dairy-free
soy-free
Uplift, Energise, and Support

